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Prof. Yonggui Zhou’s Laboratory (Team 201): Chiral Synthesis

Coordinator:

Prof. Dr. Yonggui ZHOU

Address :

457 Zhongshan Road,Dalian 116023, China

Tel:

+86-411-84379220

Fax:

+86-411-84379220

Email:

ygzhou@dicp.ac.cn

Introduction:
     Led by Prof. Dr. Yonggui ZHOU, the group was established in September 2002. At present the group consists of 2 scientists and 4 graduate students engaging on investigations of asymmetric catalysis and synthesis, with emphasis on asymmetric hydrogenation of heteroaromatic compounds and total synthesis of tetrahydroquinoline alkaloids.

Research Interests :
     Asymmetric Catalysis and Synthesis

(1) Transition metal-catalyzed asymmetric hydrogenation of heteroaromatic compounds: Asymmetric hydrogenation of heteroaromatic compounds with chiral transition metal complexes as catalysts, especially qunolines and isoquinolines.

(2) Synthesis and application of some novel chiral ligands: Synthesis of some novel chiral ligands with sulfur; Design and synthesis of some new chiral ligands based on Stacking Effects.

(3) Asymmetric total synthesis of alkaloids: Total synthesis of some quinoline and isoquinoline alkaloids based on methodology of asymmetric hydrogenation of quinolines and isoquinolines.

Researh Projects :
Asymmetric hydrogenation of heteroaromatic compounds, quinolines

Total synthesis of tetrahydroquinoline alkaloids